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December 7, 2023
Comparison of two forms of daily preventive zinc supplementation versus therapeutic zinc supplementation for diarrhea on young children’s physical growth and risk of infection: study design and rationale for a randomized controlled trial
Overview
The purpose of this study to compare different regimens of zinc supplementation used to for prevention of zinc deficiency and treatment of diarrhea.
A community-based, randomized controlled trial was used for this comparison. Children between 6-23 months old were divided into four intervention groups – daily preventive zinc dispersible tablet, daily preventive multiple micronutrient powder, therapeutic zinc dispersible tablet for diarrhea, or placebo control. The interventions were distributed for 9 months.
This study will provide evidence to support the best mechanisms delivering supplemental zinc.
Publication
BMC Nutrition